Science & tech

Why Does Cannabis Make You Laugh?

Published on December 22, 2015 · Last updated July 28, 2020

One of my favorite things about cannabis is its ability to shed a humorous light on everyday life. Like this Leafly user so eloquently puts it in a Blue Diesel review, “I laughed so hard that I threw up. And that made me laugh more. It was terrible.”

Okay, so most people won’t literally bust their guts over cannabis like this reviewer nearly did, but the point is that marijuana can make things seem hilarious, and that’s a beautiful thing whether or not your mood is in need of a boost. But as we prepare to launch Leafly’s first comedy tour in Seattle, Los Angeles, and Denver, the question occurred to us: why does cannabis make everything funnier?

T.J. Miller Kicks Off the 2016 Leafly Comedy Tour

Why Do We Laugh?

Before understanding how cannabis affects humor, it’s helpful to know what’s happening in the brain that causes laughter. Neuroscientists admit that it’s difficult to isolate specific reasons for laughter, as it involves multiple areas of the brain governing motor function, language, memory, auditory interpretation, and logic. Laughing is a motor reflex prompted by our interpretation of humor, which is a complex idea comprised of many different building blocks like our cultural, linguistic, and social contexts. MRI scans, however, have shown that humor is processed primarily in the frontal and temporal lobes of the cerebral cortex – and that’s where we start to see cannabis play its role.

Cannabis Stimulates Brain Areas Associated with Laughter

Studies show that cannabis stimulates blood flow to the right frontal and the left temporal lobes, areas of the brain which are also associated with laughter. In this way, it could be that over-activity in these cortical regions, thanks to THC, invites laughter. Could that explain why we laugh so hard even at stupid things while high? Science hasn’t revealed the extent to which that increased blood flow is directly responsible for stimulating laughter, but it’s certainly a target for future studies.

Cannabis Improves Moods

THC binds to receptors in the brain that modulate neural signaling, leading the blissful, happy effects we feel while high. A few reports, like these 2005 and 2007 studies, even suggest that cannabis compounds may promote neurogenesis in some areas of the brain for an anti-anxiety and anti-depression effect. And here’s another way to think about it: scientists have noted that the brains of depressed subjects show decreased activity in areas of the brain associated with humor, and if cannabis is able to replenish that activity, finding a good laugh is going to be easier.

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Despite the promising results of these studies, there’s a shortage of clinical trials analyzing these effects in human brains. But there’s certainly enough there to speculate a chemical link between laughter and the THC in cannabis.

Laughing is Socially Contagious

When you’re stoned and in hysterics, it’s likely that you aren’t sitting at home alone (although scrolling through this Reddit thread by myself yesterday completely contradicts this assumption). In the same way that friends might like to crack open a beer together, cannabis is a social bonding experience. So in addition to the fact that cannabis brings a boost to our mood and stimulates areas of the brain associated with laughter, simply sharing the experience with someone else can make laughing easier. Why? Because laughing is contagious.

The reasons for this are still emerging in science, but researcher Sophie Scott dedicates her studies to the social role of laughter. In a TED Talk, she explains, “It’s an enormously behaviorally contagious effect. You can “catch” laughter from somebody else, and you’re more likely to catch laughter from somebody else if you know them. It’s modulated by the social context.” In fact, you’re 30 times more likely to laugh when in the company of another.

So in summary, cannabis appears to stimulate laughter by changing blood flow in the brain and exciting related neural pathways, and the presence of loved ones seems to only make laughing fits worse. We’re waiting for research to bring conjecture to proof, but considering the difficulty in studying even its medicinal, life-changing potential, it may be a while. Until then, just appreciate the fact that cannabis helps awaken the humor in us, making life a little less stressful.

Looking for some cannabis strains that induce the giggles?

Giggly cannabis strains

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Bailey Rahn
Bailey Rahn
Bailey is a senior content manager at Leafly, specializing in strains and health. She's spent 7+ years researching cannabis products, spreading patients’ stories, and exploring healthy ways of integrating cannabis into daily life.
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